CANCER RESEARCH
To identify, characterize and determine the structure of multi-subunit
macromolecular complexes involved in cancer onset or development
To provide the first nanoscale map of cancer cells, at different steps of
the metastasis cascade, from tumor initiation to metastasis formation
This consortium is composed of 13 teams, working on four axes:
Axis 1: Molecular and structural description of multiprotein complexes initiating the oncogenic process – A. Hamiche & P. Schultz
Axis 2: Establishment of a subcellular morphological atlas during carcinogenesis: From
organelles to molecular networks that drive cancer – K. Schauer & V. Hyenne
Axis 3: Biosensors, protein and chemical inhibitors – P. Martineau & M. Tramier
Axis 4: In vivo integration of targetable candidate protein complexes in patient samples – J.P.Borg & L. Camoin
